How do embryos establish reproducible spatial patterns of gene expression from stochastic transcription?
Histone variant H2A.B-H2B dimers are spontaneously exchanged through the open conformation with canonical H2A-H2B in the nucleosome
Elucidation of the role of a protein that supports the matching of paternal and maternal chromosomes in meiosis
Elucidation of the mechanism by which cGAS, a foreign DNA sensor of innate immunity, does not respond to self chromosomal DNA
Successful development of technology for simultaneous detection of multiple epigenomic information from the same cell