会場：東京大学定量生命科学研究所 生命科学総合研究棟 B棟301号室
講師：竹俣 直道 博士（postdoctoral fellow，Stephen D. Bell Lab，Indiana University）
演題：Evolution of chromosome folding: insights from archaea
Very little is known about the folding principles of chromosomes in the Archaea, the closest prokaryotic relatives of eukaryotes. By performing Hi-C, we have recently shown that chromosomes of Sulfolobus archaea are organized into eukaryotic A/B compartment-like structures. The compartmentalization of the Sulfolobus chromosomes is driven by a hitherto uncharacterized SMC protein that we named “coalescin.” On the basis of our findings and other studies, I will discuss common and unique features of chromosome folding between the three domains of life.